Control of microbial growth with lantibiotic/lysozyme formulations
AssigneeHaarman & Reimer GmbH
InventorDaniel J. Monticello
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Abstract
Disclosed is a method of inhibiting procaryotic microbial growth which method involves adding a synergistically effective combination of a lantibiotic and lysozyme to an environment in which such microbial growth is to be inhibited.
Claims16
A method for lysing Listeria monocytogenes in a composition containing said bacteria comprising adding to said composition a synergistically effective amount of
- a) a lantibiotic selected from the group consisting of nisin and subtilin;
- and
- b) lysozyme;
- to effect lysis of said bacteria.
A method of lysing Listaria monocytogenes in foodstuffs comprising adding to the foodstuffs a combination of a lantibiotic selected from the group consisting of nisin and subtilin and lysozyme wherein the lantibiotic is provided in an amount from 100 to 2000 IU/ml and the lantibiotic and lysozyme is present in a ratio of from 9 IU/ml:1 .mu.g/ml to 1 IU/ml:2 .mu.g/ml of lantibiotic:lysozyme.
A method of lysing Listaria monocytogenes in a composition containing said bacteria which comprises adding to said composition a synergistically effective amount of a combination of about 100 IU nisin and about 10 .mu.g/ml lysozyme while maintaining the temperature of the composition at about 37.degree. C. and the pH at from about 6.5 to 8.5.
Dependencies are inferred from the claim text.