Embolization plugs for blood vessels
AssigneeVitaphore Corporation
InventorsStanley R. Conston, Gregory S. Dapper, Aileen L. Murphy, Jennifer Raeder-Devens, Ronald Yamamoto
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Abstract
A bioresorbable and hemostatic plug for embolization made from a collagen piece is compressed so as to be longitudinally insertable into a tubular biological vessel such as a blood vessel to be occluded. The collagen piece is capable of expanding radially inside the vessel by absorbing fluid such as the blood and thereby providing mechanical fixation in and occlusion of the vessel. Two such collagen pieces may be used with a spacer of a different material in between. Different kinds of therapeutic agents can be bonded to or physically absorbed by the collagen pieces so as to be delivered to the site of occlusion.
Claims21
A plug which, in a compressed condition, is longitudinally insertable into a tubular biological vessel, said plug comprising a piece having unconstrained dimension greater than the inner diameter of said vessel, said piece having a modulus at 60% compression greater than 0.15 g/mm.sup.2 and being capable of expanding radially inside said vessel by absorbing fluid and thereby providing mechanical fixation in and occlusion of said vessel.
A plug which is compressible and is longitudinally insertable into a tubular biological vessel when in a compressed condition, said plug comprising a piece having unconstrained dimension greater than the inner diameter of said vessel, said piece comprising bioerodible material with a controllable rate of bioresorption, having a modulus at 60% compression greater than 0.15 g/mm.sup.2 and being capable of expanding radially inside said vessel by absorbing fluid and thereby providing mechanical fixation in and occlusion of said vessel.
Dependencies are inferred from the claim text.