Substituted cyclohexane derivatives for the treatment of diseases

A cyclohexane derivative of the formula I ##STR67## in which A--B is the group ##STR68## or the group ##STR69## R.sup.1 is:

• CN, COOH, COO--(C.sub.1 -C.sub.4 -alkyl), C.sub.1 -C.sub.4 -alkanoyl, SO.sub.3 --(C.sub.1 -C.sub.4 -alkyl), SO.sub.3 H, PO(OH).sub.2, PO(OH) (O--C.sub.1 -C.sub.4 -alkyl) or PO(O--C.sub.1 -C.sub.4 -alkyl).sub.2,
• R.sup.2 is:
• H, OH or F,
• R.sup.3 is:
• H, phenyl, naphthyl, pyridyl, thienyl or furyl, where the aromatic or heteroaromatic system can be monosubstituted or polysubstituted by F, Cl, Br, I, OH, NO.sub.2, C.sub.1 -C.sub.4 -alkanoyl, C.sub.1 -C.sub.4 -alkoxy, C.sub.1 -C.sub.4 -alkyl, phenyl, phenoxy, thienyl, furyl, pyridyl, imidazolyl or benzyloxy, where the substituents are identical or different,
• R.sup.4, R.sup.5 and R.sup.6 are:
• H, OH, F, Cl, Br, C.sub.1 -C.sub.4 -alkanoyl, C.sub.1 -C.sub.4 -alkyl, phenyl, phenoxy, thienyl, furyl, pyridyl, imidazolyl or benzyloxy, where R.sup.4, R.sup.5 and R.sup.6 are identical or different,
• X is:
• --(CH.sub.2).sub.n --, --CH.dbd.CH-- or --CH.sub.2 OCH.sub.2 --,
• Y is:
• --(CH.sub.2).sub.n --,O, S or NH,
• Z is:
• --(CH.sub.2).sub.n -- or --CH.dbd.CH-- and
• n is:
• zero, 1, 2, 3 or 4 for inhibition of the glucose-6-phosphatase system of the liver in mammals.