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US 5,451,321 AGranted
Venting system
AssigneePall Corporation
InventorVlado I. Matkovich
Life of this patent
Estimating the term…
Abstract
Biological fluid processing assemblies having a gas inlet and/or a gas outlet are disclosed.
Claims60
A filtration system for the filtration of blood or a blood component comprising:
- a container for containing the blood or the blood component to be filtered;
- a receiving container for receiving the filtered blood or the blood component;
- a transfer line communicating between said container for the blood or the blood component to be filtered and said receiving container;
- a leukocyte depletion filter capable of filtering said blood or said blood component carried in said transfer line between said container for the blood or the blood component to be filtered and said receiving container;
- and
- a gas outlet carried in said transfer line downstream of said filter and upstream of said receiving container, said gas outlet including:
- (a) a housing;
- (b) a first microporous membrane having first and second sides and being positioned in said housing with said first side in communication with said transfer line, said first microporous membrane being wettable by the filtered blood or the filtered blood component;
- and
- (c) a second microporous membrane superimposed on said second side of said first microporous membrane, said second microporous membrane being capable of permitting gas to pass therethrough, said first and second microporous membranes arranged to permit the gas to be vented from the gas outlet while said first microporous membrane remains unwetted with blood or blood component, and to permit said gas outlet to be sealed when said first microporous membrane is wetted with blood or blood component.
7 more elements
A closed system for the transfer of a biological fluid comprising:
- a collapsible reservoir which contains the biological fluid to be transferred;
- a receiving container for receiving the transferred biological fluid:
- a transfer line in communication with said collapsible reservoir and with said receiving container;
- a leukocyte depletion filter capable of leukocyte depleting said biological fluid carried in said transfer line between said reservoir and said receiving container;
- and
- a gas outlet carried in said transfer line downstream of said filter and upstream of said receiving container, said gas outlet including:
- (a) a housing;
- (b) a first microporous membrane having first and second sides and being positioned in said housing with said first side in communication with said transfer line, said first microporous membrane being liquid-wettable by the biological fluid to be transferred in said system;
- and
- (c) a second microporous membrane superimposed on said second side of said first microporous membrane, said second microporous membrane being capable of permitting gas to pass therethrough, said first and second microporous membranes arranged to permit, the gas to be vented from said gas outlet while said first microporous membrane remains unwetted with biological fluid, and to permit said gas outlet to be sealed when said first microporous membrane is wetted with biological fluid.
7 more elements
A method for processing a biological fluid comprising:
- passing a biological fluid through a leukocyte depletion device;
- opening at least one gas inlet comprising a porous medium;
- and
- driving the biological fluid through the leukocyte depletion device by allowing gas to flow into the gas inlet.
1 more element
The method of 26 further comprising opening a gas inlet coupled to the leukocyte depletion device.
A method for processing blood or a blood product comprising:
- passing the blood or blood product through a leukocyte depletion medium;
- passing gas displaced by the blood or blood product through a gas outlet comprising a porous medium until the blood or blood product contacts the porous medium;
- and,
- passing gas through a gas inlet comprising a porous medium to drive additional blood or blood product through the leukocyte depletion medium.
1 more element
A system for processing blood or a blood component comprising:
- a leukocyte depletion filter;
- a container for receiving leukocyte depleted blood or blood component, said container located downstream of the filter;
- a gas collection arrangement in fluid communication with the upstream of the filter and the downstream of the filter, said gas collection arrangement including a gas container and a porous medium for passing gas therethrough, said porous medium comprising a membrane liquophobic to the blood or the blood component.
Dependencies are inferred from the claim text.