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US 5,447,966 AGranted
Treating bioabsorbable surgical articles by coating with glycerine, polalkyleneoxide block copolymer and gelatin
AssigneeUnited States Surgical Corporation
InventorsMatthew E. Hermes, Ross R. Muth, Darel L. Gustafson
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Abstract
An absorbable composition useful for treating absorbable surgical devices to render the same storage stable and/or to enhance delivery of the article and/or a medico-surgically useful substance to a wound. The preferred composition includes collagen or a derivative thereof, a plasticizer and a surfactant.
Claims13
A storage stable, bioabsorbable surgical device possessing improved storage stability and formed from a molded bioabsorbable article coated with a bioabsorbable composition, the composition comprising:
- (i) about 98% to about 60% by weight gelatin;
- (ii) about 1% to about 30% by weight of a plasticiser dispersed or dissolved in (i) said gelatin, wherein said plasticizer is a water-soluble hygroscopic polyhydroxy compound or ester derivative thereof;
- and
- (iii) about 0.1% to about 25% by weight of a polyethylene oxide-polypropylene oxide block copolymer surfactant dispersed or dissolved in (i) said gelatin or in (ii) said plasticizer;
- wherein said surgical device is a surgical clip, stable, pin, screw, or tac fabricated in whole or in part from a polymer or copolymer of gylcolic acid, lactic acid, glycolide, lactide, dioxanone, trimethylene carbonate, caprolactone, polyalkylene glycol or combination thereof.
2 more elements
Dependencies are inferred from the claim text.