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US 5,444,105 AGranted
Specimen mounting adhesive composition
AssigneeMount Sinai School of Medicine of the City University of New York
InventorLeonard Ornstein
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AssigneeMount Sinai School of Medicine of the City University of New York
InventorLeonard Ornstein
Estimating the term…
A composition is disclosed for transferring and adhering tape-mounted hisogical sections, to specimen mounting surfaces, usually glass microscope slides to expedite and simplify the safe removal of the mounting tape and the subsequent processing of the slide-mounted section. The composition is a curable polymeric mixture which has high tack prior to curing, is substantially non-diffusable and non-flowable into tissue sections and, after curing, has a refractive index substantially similar to that of the specimen section and is non-labile to conventional histological solvents and stains. A preferred composition comprises diacrylate-terminated polyurethane, a diacrylate ester of an epoxy resin and a diethoxyacetophenone initiator. It is usually formed onto the mounting surface as a solution in a conventional organic solvent, such as isopropanol or toluene.
A highly viscous and substantially indiffusible curable adhesive composition for transferring and mounting a tape-supported thin histological tissue section onto a specimen support for further processing, comprising a high molecular weight polymerizable component wherein said component contains one or more high molecular weight polymerizable interractive difunctional oligomers selected from acryl or methacryl esters of epoxy resins or mixtures thereof with acryl- or methacryl-terminated polyurethane resins, and a polymerization curing initiator therefor, which polymerized composition is characterized in that before cure:
A highly viscous and substantially indiffusible curable unpolymerized adhesive composition for transferring and mounting a tape-supported thin histological tissue section onto a specimen support for further processing, comprising a mixture of diacrylate-terminated urethane and a diacrylate ester of an epoxy resin in a weight ratio of 1:2 to about 1:3 respectively, said composition further comprising a polymerizable curing initiator therefor, which composition is characterized in that before cure:
Dependencies are inferred from the claim text.