Method of treating certain tumors using illudin analogs
AssigneeThe Regents of the University of California
InventorsMichael J. Kelner, Trevor C. McMorris, Raymond Taetle
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Abstract
A therapeutic method is provided to inhibit tumor cell growth in a subject in need of said therapy is provided, comprising parenterally administering a therapeutic amount of a compound in a pharmaceutically acceptable carrier, wherein said compound has the structure: ##STR1## wherein R is selected from the group consisting of: ##STR2## and wherein said tumor cell is sensitive to inhibition by said compound and is selected from the group consisting of a myeloid leukemia cell, a T-cell leukemia cell, a lung carcinoma cell, an ovarian carcinoma cell, and a breast carcinoma cell.
Claims12
A therapeutic method of inhibiting rumor cell growth in a subject in need of said therapy comprising parenterally administering a therapeutic amount of a compound in a pharmaceutically acceptable carrier, wherein said compound has the structure:
- ##STR18## wherein R is selected from the group consisting off ##STR19## and wherein said rumor cell is sensitive to inhibition by said compound and is selected from the group consisting of a myeloid leukemia cell, a T-cell leukemia cell, a lung carcinoma cell, an ovarian carcinoma cell, and a breast carcinoma cell.
Dependencies are inferred from the claim text.