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US 5,439,924 AGranted
Systemic control of parasites
AssigneeVirbac
InventorThomas A. Miller
Life of this patent
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AssigneeVirbac
InventorThomas A. Miller
Estimating the term…
The present invention is a method for controlling ectoparasites. More particularly, the invention relates to a method of treatment in which the warm blooded animal is dosed with an ovicidally effective amount of a heterocyclic nitrogen compound selected from the group represented by the formula: ##STR1## wherein R.sub.1, is either one of the following groups: ##STR2## R.sub.2 and R.sub.3 are the same or different, each a hydrogen atom, a halogen atom or a methyl group; R.sub.4 is a halogen atom or a methyl group; R.sub.5 and R.sub.6 are the same or different, each a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.4 haloalkyl group or a C.sub.1 -C.sub.4 haloalkoxy group; X, Y and Z are the same or different, each an oxygen atom, a sulfur atom or a methylene group, which is transmitted to the ectoparasite by the animal's blood. In a further embodiment, a compound selected from the group consisting of ivermectin, milbemycin, milbemycin oxime, moxidectin and avermectin and avermectin derivatives.
A method for the systemic control of ectoparasites which attack warm blooded animals, comprising administering to a warm blooded animal a systemic periodic dose in the range of 0.001 mg to 1000 mg of compound per kilogram of animal body weight of a compound having the formula:
A method of systemically controlling ectoparasites and endoparasites in warm blooded animals which comprises administering a single dose in the range of about 10 to 200 mg/kg of 2-[1-methyl-2-(-4-phenoxyphenoxy)ethoxy]pyridine (pyriproxifen) formulated to deliver an ovicidally effective amount to the animals blood stream for at least 25 days and 0.5 mcg/kg to 100 mg/kg of a parasite control compound selected from the group consisting of milbemycin, milbemycin derivatives, ivermectin, ivermectin derivatives, milbemycin oxime, milbemycin oxime derivatives, moxidectin, moxidectin derivatives, avermectin, and avermectin derivatives, or mixtures thereof, to a warm blooded animal such that ectoparasites feeding on the blood of the animal receive an ovicidally effective amount of pyriproxifen for at least 25 days.
A method of preventing the propagation of fleas which comprises the step of providing the adult fleas with nutrient blood which contains an ovicidally effective amount of pyriproxifen.
Dependencies are inferred from the claim text.