Dextrin sulfates as anti HIV-1 agents and composition thereof
AssigneeML Laboratories PLC
InventorDonald S. Davies
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Abstract
The invention provides an agent against HIV-1 and related viruses, the agent being or including dextrin sulphate containing at most two sulphate groups per glucose unit. The invention also provides a composition containing such an agent, and the use of the agent or composition against HIV-1 and related viruses. By restricting the degree of substitution of the dextrin sulphate to a maximum of 2, the invention makes it possible to produce a dextrin sulphate having adequate anti-HIV activity while maintaining toxicity within acceptable limits.
Claims13
An agent against HIV-1 and related viruses, the agent being or including dextrin sulphate containing at most two sulphate groups per glucose unit, and wherein the weight average molecular weight of the dextrin sulphate varies from 15,000 to 25,000.
An agent against HIV-1 and related viruses, the agent being or including dextrin sulphate containing at most two sulphate groups per glucose unit, and wherein the weight average molecular weight of the dextrin sulphate is at least 15,000.
Dependencies are inferred from the claim text.