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US 5,439,684 AGranted
Shaped, swollen demineralized bone and its use in bone repair
AssigneeOsteotech, Inc.
InventorsAnnamarie B. Prewett, Roger C. Stikeleather, Simon Bogdansky, Robert K. O'Leary
Life of this patent
Estimating the term…
Abstract
A shaped piece of swollen demineralized bone which can also be plasticized is provided for use in surgical bone repair.
Claims26
A kit for swelling, disinfecting and/or plasticizing demineralized bone, said kit comprising
- (a) a first sealed vessel comprising the bone immersed in a swelling medium,
- (b) a second sealed vessel comprising disinfecting and/or plasticizing medium, and
- (c) means for accessing the interior of said first vessel for (1) draining off said swelling medium and (2) placing said first sealed vessel in open communication with said second sealed vessel containing said disinfecting and/or plasticizing medium,
- wherein said swelling medium is selected from a member of the group consisting of liquid polyhydroxy compound, liquid polyhydroxy compound ester, liquid solution of solid polyhydroxy compound, liquid solution of solid polyhydroxy compound ester and mixtures thereof, and
- the polyhydroxy compound is selected from the group consisting of acyclic polyhydric alcohols, non-reducing sugars, sugar alcohols, sugar acids, monosaccharides, disaccharides, water-soluble or water dispersible oligosaccharides, polysaccharides, polyalkylene glycols and mixtures thereof.
2 more elements
A kit for swelling, disinfecting and/or plasticizing demineralized bone, said kit comprising
- (a) a first sealed vessel comprising the bone immersed in a swelling medium,
- (b) a second sealed vessel comprising disinfecting and/or plasticizing medium, and
- (c) means for accessing the interior of said first vessel for (1) draining off said swelling medium and (2) placing said first sealed vessel in open communication with said second sealed vessel containing said disinfecting and/or plasticizing medium,
- wherein the swelling medium is selected from the group consisting of ethylene glycol, diethylene glycol, triethylene glycol, 1,2-propanediol, trimethylolethane, trimethylopropane, erythritol, pentaerythritol, polyethylene glycols, xylitol, sorbitol, mannitol, dulcitol, arabinose, xylose, ribose, adonitol, arabitol, rhamose, inositol, fructose, galactose, glucose, mannose, sorbose, sucrose, maltose, lactose, maltitol, lactitol, stachyose, maltopentaose, cyclomaltohexaose, carrageenan, agar, alginic acid, guar gum, gum tragacanth, locust bean gum, gum arabic, xanthan gum, amylose and mixtures thereof.
1 more element
Dependencies are inferred from the claim text.