Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction
OwnerPankai J. Pasricha, Anthony N. Kallooinventors
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OwnerPankai J. Pasricha, Anthony N. Kallooinventors
Estimating the term…
Direct injection of sphincteric botulinum toxin is disclosed as an effective, safe and simple method of treatment for disorders of gastrointestinal muscle or smooth muscles elsewhere in the body, with results that appear to be sustained for several months. Muscle disorders which are suitable for such treatment include achalasia, isolated disorders of the lower esophageal sphincter, gastroparesis, hypertrophic pyloric stenosis, sphincter of Oddi dysfunction, short-segment Hirschsprung's, anal fissure, hemorrhoids, proctalgia fugax, irritable bowel syndrome, disorders of the upper esophageal sphincter, vasospastic disorders, and disorders of uterine and bladder spasm. Devices suitable for delivering this therapy are also disclosed.
A method for in vivo treatment of smooth muscle disorders of a mammal, comprising:
A method for in vivo treatment of disorders of a gastrointestinal muscle in the enteric nervous system of a mammal, comprising:
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