Organic nitrates and method for their preparation

Compounds of the formula ##STR6## wherein:

• R represents hydroxy, lower alkoxy, lower alkenoxy, di-lower alkylamino-lower alkoxy, acylamino-lower alkoxy, acyloxy-lower alkoxy, aryloxy, aryl-lower alkyloxy, substituted aryloxy or substituted aryl-lower alkoxy groups, where the substituent is a member of the group consisting of methyl, methoxy and halogen;
• amino, lower alkylamino, di-lower alkylamino, aryl-lower alkylamino, hydroxy-lower alkylamino or amino acid groups through peptide bonds,
• R.sup.1 represents hydrogen, alkyl with 1 to 6 carbon atoms, substituted lower alkyl, where the substituent is a member of the group consisting of halogen, groups defined by R containing hydroxy, lower alkoxy, aryloxy, amino, lower alkylamino, acylamino, acyloxy, arylamino, mercapto, lower alkylthio and arylthio,
• R.sup.2 represents hydrogen, lower alkyl and the groups represented by R.sup.1,
• R.sup.3 represents hydrogen and lower alkyl,
• R.sup.4 represents hydrogen, lower alkyl, phenyl, methoxyphenyl, phenyl-lower alkyl, methoxyphenyl-lower alkyl, hydroxyphenyl-lower alkyl, hydroxy lower alkyl, alkoxy lower alkyl, amino-lower alkyl, acylamino lower alkyl, mercapto-lower alkyl and lower alkylthio-lower alkyl,
• R.sup.5 represents lower alkylthiol, --SH and S-acyls of alkylthiol and --SH and particularly --S-acetyl, --S-propionyl, --S-butyryl, --S-isobutyryl, --S-caproyl, --S-capryl, --S-pivaloyl and --S-benzoyl, lower alkyl --S--C--O--R.sup.6, lower alkyl --S--C--N--R.sup.6, lower alkylthio-lower alkanoic acid and esters and amides thereof, and lower alkylthio-lower alkyl, wherein R.sup.6 represents hydrogen and lower alkyl,
• groups in which R and R.sup.5 are bonded together and form part of a thiolactone group,
• m, n and q are whole numbers from 0 to 10,
• p is 0 or 1, and
• pharmaceutically acceptable salts thereof.