Dosage form for micro-bubble echo contrast agents
AssigneeByk Gulden Lomberg Chemische Fabrik GmbH
InventorKlaus-Dieter Beller
Life of this patent
Estimating the term…
Abstract
A dosage form for micro bubble echo contrast media which comprises a syringe (6) and a mixing chamber (1) which is connected thereto and contains a predetermined amount of gas, plus a second syringe is described. The novel dosage form allows easy, standardised preparation of echo contrast media and gives high contrast (FIG. 3).
Claims23
A combination of a) means for generating micro bubbles in an echo contrast medium with b) a mixing chamber and c) a predetermined amount of sterile gas, wherein the means is a syringe which has an outlet sealed to the mixing chamber which contains the predetermined amount of sterile gas.
Apparatus useful for preparing micro bubble echo contrast media and comprising a first syringe, a mixing chamber and a second syringe;
- the mixing chamber having an inlet, an outlet, an inner lumen and a predetermined amount of sterile gas in the inner lumen;
- the first syringe comprising a barrel and having an outlet sealed to the inlet of the mixing chamber;
- and the second syringe having an outlet means for connecting it to the outlet of the mixing chamber.
Apparatus useful for preparing micro bubble echo contrast media and comprising a first syringe, a mixing chamber and a second syringe;
- the mixing chamber having an inlet, an outlet, one or more perforated diaphragms, an inner lumen and a plurality of mixing elements in the inner lumen;
- the first syringe comprising a barrel and having an outlet sealed to the inlet of the mixing chamber;
- and the second syringe having outlet means for connecting it to the outlet of the mixing chamber.
Apparatus useful for preparing micro bubble echo contrast media and comprising a first syringe, a mixing chamber and a second syringe;
- the mixing chamber having a inlet, an outlet, an inner lumen and a plurality of mixing elements, in the form of spikes, in the inner lumen;
- the first syringe comprising a barrel and having an outlet sealed to the inlet of the mixing chamber;
- and the second syringe having outlet means for connecting it to the outlet of the mixing chamber.
Apparatus useful for preparing micro bubble echo contrast media and comprising a first syringe, a mixing chamber and a second syringe;
- the mixing chamber having an inlet, an outlet, an inner lumen and a plurality of mixing elements, in a mutually offset helical arrangement, in the inner lumen;
- the first syringe comprising a barrel and having an outlet sealed to the inlet of the mixing chamber;
- and the second syringe having outlet means directly connected to the outlet of the mixing chamber.
Apparatus useful for preparing micro bubble echo contrast media and comprising a first syringe, a mixing chamber and a second syringe;
- a mixing chamber having an inlet, an outlet, an inner lumen and a plurality of mixing elements in the inner lumen;
- the first syringe comprising a barrel and having an outlet sealed to the inlet of the mixing chamber;
- and the second syringe containing a liquid contrast medium component and having outlet means directly connected to the outlet of the mixing chamber.
Dependencies are inferred from the claim text.