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AssigneeMeito Sangyo Kabushiki Kaisha
InventorsMasakatsu Hasegawa, Hideo Nagae, Yoshio Ito, Akihiro Mizutani, Kimio Hirose, Masahiro Ohgai, Yasuji Yamashita, Nahoko Tozawa, Keiko Yamada, Kyoji Kito, Shusaburo Hokukoku
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An oxidized complex comprising a water-soluble carboxypolysaccharide and magnetic iron oxide, which is characterized by being obtained by oxidizing a complex comprising a water-soluble carboxypolysaccharide and magnetic iron oxide. Said oxidized complex has very low toxicity, is very stable, exhibits little or no blood pressure-reducing action and has low platelets-aggregating action when administered directly into the blood vessels of animals, and is useful in medical fields such as contrast medium for magnetic resonance imaging, exothermic medium for hyperthermia and the like.
A complex comprising a water-soluble carboxypolysaccharide selected from the group consisting of carboxydextran and carboxystarch, and magnetic iron oxide ultrafine particles having a particle diameter of about 2 to about 30 nm, the proportion of bivalent iron to total iron in the complex being in the range of 0 to about 7%, the complex having a magnetism of 10-150 emu per g of iron at 1 T;
Dependencies are inferred from the claim text.