Devices for detection of an analyte based upon light interference

An optical assay device comprising an optically active receptive surface comprising a thin interference film, an attachment layer on top of said interference film, wherein said attachment layer comprises a star polymer, and a layer containing specific binding reagents to an analyte of interest attached to said attachment layer, wherein said surface is supported on a pedestal that is held within a first container;

• wherein said first container comprises a first absorbent material bordering said pedestal where said pedestal contacts said first container, wherein said first absorbent material is configured and arranged to absorb liquid draining from said surface, and
• a second container, hingedly connected to one side of said first container, said second container comprising a second absorbent material, wherein said second container can be closed to said first container by rotation about the hinge, and wherein such closing causes said second absorbent material to contact said surface.

An optical assay device comprising an optically active receptive surface comprising a thin interference film, an attachment layer on top of said interference film, wherein said attachment layer comprises a molecular self-assembling polymer, and a layer containing specific binding reagents to an analyte of interest attached to said attachment layer, wherein said surface is supported on a pedestal that is held within a first container;

• wherein said first container comprises a first absorbent material bordering said pedestal where said pedestal contacts said first container, wherein said first absorbent material is configured and arranged to absorb liquid draining from said surface, and
• a second container, hingedly connected to one side of said first container, said second container comprising a second absorbent material,.wherein said second container can be closed to said first container by rotation about the hinge, and wherein such closing causes said second absorbent material to contact said surface.

An optical assay device comprising an optically active receptive surface comprising a thin interference film;

• an attachment layer on Cop of said interference film, wherein said attachment layer comprises a polymeric siloxane, and a layer containing specific binding reagents to an analyte of interest attached to said attachment layer, wherein said surface is supported on a pedestal that is held within a first container;
• wherein said first container comprises a first absorbent material adjacent said pedestal where said pedestal contacts said first container, wherein said first absorbent material is configured and arranged to absorb liquid draining from said surface, and
• a second container, hingedly connected to one side of said first container, said second container comprising a second absorbent material, wherein said second container can be closed to said first container by rotation about the hinge, and wherein such closing causes said second absorbent material to contact said surface.

An optical assay device comprising an optically active receptive surface comprising a thin interference film, an attachment layer on top of said interference film, wherein said attachment layer comprises a siloxane, and a layer containing specific binding reagents to an analyte of interest attached to said attachment layer, wherein said surface is supported on a pedestal that is held within a first container;

• wherein said first container comprises a first absorbent material bordering said pedestal where said pedestal contacts said first container, wherein said first absorbent material is configured and arranged to absorb livid draining from said surface, and
• a second container, hingedly connected to one side of said first container, said second container comprising a second absorbent material, wherein said second container can be closed to said first container by rotation about the hinge, and wherein such closing causes said second absorbent material to contact said surface.

An optical assay device comprising an optically active receptive surface comprising a thin interference film, an attachment layer on top of said interference film, wherein said attachment layer comprises a film forming latex, and a layer containing specific binding reagents to an analyte of interest attached to said attachment layer, wherein said surface is supported on a pedestal that is held within a first container;

• wherein said first container comprises a first absorbent material bordering said pedestal where said pedestal contacts said first container, wherein said first absorbent material is configured and arranged to absorb liquid draining from said surface, and
• a second container, hingedly connected to one side of said first container, said second container comprising a second absorbent material, wherein said second container can be closed to said first container by rotation about the hinge, and wherein such closing causes said second absorbent material to contact said surface.

An optical assay device, comprising a plurality of optically active receptive surfaces, wherein each optically active receptive surface comprises a thin interference film, an attachment layer on top of said interference film, wherein said attachment layer comprises a dendrimer, and a layer containing specific binding reagents to an analyte of interest attached to said attachment layer, supported on a base, said base comprising a first absorbent material configured and arranged to absorb liquid draining from said surfaces, and

• a slidable lid comprising one or more absorbent regions configured and arranged to contact said optically active surfaces during use of the device.

An optical assay device, comprising a plurality of optically active receptive surfaces, wherein each optically active receptive surface comprises a thin interference film, an attachment layer on top of said interference film, wherein said attachment layer comprises a star polymer, and a layer containing specific binding reagents to an analyte of interest attached to said attachment layer, supported on a base, said base comprising a first absorbent material configured and arranged to absorb liquid draining from said surfaces, and

• a slidable lid comprising one or more absorbent regions configured and arranged to contact said optically active surfaces during use of the device.

An optical assay device, comprising a plurality of optically active receptive surfaces, wherein each optically active receptive surface comprises a thin interference film, an attachment layer on top of said interference film, wherein said attachment layer comprises a molecular self-assembling polymer, and a layer containing specific binding reagents to an analyte of interest attached to said attachment layer, supported on a base, said base comprising a first absorbent material configured and arranged to absorb liquid draining from said surfaces, and

• a slidable lid comprising one or more absorbent regions configured and arranged to contact said optically active surfaces during use of the device.

An optical assay device, comprising a plurality of optically active receptive surfaces, wherein each optically active receptive surface comprises a thin interference film, an attachment layer on top of said interference film, wherein said attachment layer comprises a polymeric siloxane, and a layer containing specific binding reagents to an analyte of interest attached to said attachment layer, supported on a base, said base comprising a first absorbent material configured and arranged to absorb liquid draining from said surfaces, and

• a slidable lid comprising one or more absorbent regions configured and arranged to contact said optically active surfaces during use of the device.

An optical assay device, comprising a plurality of optically active receptive surfaces, wherein each optically active receptive surface comprises a thin interference film, an attachment layer on top of said interference film, wherein said attachment layer comprises a siloxane, and a layer containing specific binding reagents to an analyte of interest attached to said attachment layer, supported on a base, said base comprising a first absorbent material configured and arranged to absorb liquid draining from said surfaces and

• a slidable lid comprising one or more absorbent regions configured and arranged to contact said optically active surfaces during use of the device.

An optical assay device, comprising a plurality of optically active receptive surfaces, wherein each optically active receptive surface comprises a thin interference film, an attachment layer on top of said interference film, wherein said attachment layer comprises a film forming latex, and a layer containing specific binding reagents to an analyte of interest attached to said attachment layer, supported on a base, said base comprising a first absorbent material configured and arranged to absorb liquid draining from said surfaces, and

• a slidable lid comprising one or more absorbent regions configured and arranged to contact said optically active surfaces during use of the device,