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AssigneeAlfatec-Pharma GmbH
InventorsJens-Christian Wunderlich, Ursula Schick, Jurgen Freidenreich, Jurgen Werry
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The invention is directed to exactly dosable molded particles, for example granulates or pellets comprising hydrophilic macromolecules, active materials and additionally further pharmaceutically acceptable skeleton formers and additives wherein the active substance is provided to the matrix, dissolved, suspended or emulsified and a new process for the preparation of such molded particles wherein the process is particularly economically and ecologically unburdensome, as well as the use of such molded particles as pharmaceuticals in which the bioavailability, shelf life, and acceptability ar improved. Furthermore, by means of the molded particles of the present invention, mixtures, intermediates, and end products may be provided for the fields of pharmacy, cosmetics, diagnostics, and analysis and dietetics (health care).
Pharmaceutically active substance containing dried cryopellets comprising at least one active substance, the amount and activity whereof being essentially undiminished by the cryopelleting, dispersed in a matrix, at least 50% w/w whereof comprising substantially of skeleton forming water soluble hydrophilic macromolecular material selected from the group consisting of:
Mixture comprising at least one pharmaceutically active substance and a skeleton forming water soluble hydrophilic macromolecular material at least 50% w/w where of is a member selected from the group consisting of:
Dependencies are inferred from the claim text.