Fluorescent marker components and fluorescent probes
AssigneeDiatron Corporation
InventorPeter O. G. Arrhenuis
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Abstract
Marker components are provided which are compatible with aqueous solutions, exhibit favorable fluorescence properties and exhibit decreased non-specific binding to macromolecules in solution. These marker components are useful in applications such as fluorescence immunoassays, in vivo imaging and in vivo tumor therapy.
Claims22
A detectably labelled marker component which comprises a fluorophore moiety which is linked to one or more solubilizing polyoxyhydrocarbyl moieties wherein said solubilizing polyhydrocarbyl moieties are selected from a polyether, a polyol, or a water soluble polymer and wherein said fluorophore moiety is a porphyrin derivative or an azaporphyrin derivative wherein one or more bridging carbon atoms has been replaced by nitrogen.
A marker component which is compound VIII of Example 6 and FIG. 1.
Dependencies are inferred from the claim text.