Chemical prevention or reversal of cataract by phase separation inhibitors
AssigneeOculon Corporation
InventorsJohn I. Clark, Kerry W. Fowler, Mark W. Orme, Louis J. Theodore
Life of this patent
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Abstract
The present invention relate to methods and pharmaceutical reagents for decreasing the phase separation temperature and inhibiting the formation of high molecular with aggregates in eye lenses, thereby inhibiting or reversing cataract formation.
Claims16
A compound having the following formula:
- ##STR18##
A compound having the following formula:
- ##STR19##
A compound having the following formula:
- ##STR20##
A compound having the following formula:
- ##STR21##
A compound having the following formula:
- ##STR22##
A compound having the following formula:
- ##STR23##
A compound having the following formula:
- ##STR24##
A compound having the following formula:
- ##STR25##
A compound having the following formula:
- ##STR26##
A compound having the following formula:
- ##STR27##
A compound having the following formula:
- ##STR28##
A compound having the following formula:
- ##STR29##
A compound having the following formula:
- ##STR30##
A method for inhibiting cataractogenisis in the lens of an eye of a patient, which comprises administering to the patient a therapeutically or prophylactically effective amount of a compound selected from the group consisting of the following formulas:
- ##STR31##
A method for inhibiting cataractogenisis in the lens of an eye of a patient, which comprises administering to the patient a therapeutically or prophylactically effective amount of a compound selected from the group consisting of the following formulas:
- ##STR32##
A method for inhibiting cataractogenisis in the lens of an eye of a patient, which comprises administering to the patient a therapeutically or prophylactically effective amount of a compound selected from the group consisting of the following formulas:
- ##STR33##
Dependencies are inferred from the claim text.