4-hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives
AssigneeElf Sanofi
InventorsJean Gubin, Henri Inion
Life of this patent
Estimating the term…
Abstract
The subject of the invention is 4-hydroxyphenylthio derivatives of general formula: ##STR1## in which: R.sub.1 and R.sub.2, which are identical or different, each represent hydrogen, a methyl or ethyl radical or a halogen atom, R represents a (C.sub.1 -C.sub.6) alkyl, (C.sub.3 -C.sub.6) cycloalkyl or phenyl radical, R.sub.3 represents hydrogen or a halogen atom, X represents --O--, --S-- or --NR.sub.4 -- in which R.sub.4 represents hydrogen or a (C.sub.1 -C.sub.4) alkyl group, useful as synthetic intermediates, especially for the preparation of aminoalkoxyphenylsulphonyl derivatives which are pharmaceutically active compounds.
Claims6
A 4-Hydroxyphenylthio compound of the general formula:
- ##STR10## in which:
- R.sub.1 and R.sub.2, which are identical or different, are selected from the group consisting of hydrogen, methyl, ethyl and halogen
- R is selected from the group consisting of (C.sub.1 -C.sub.6)alkyl, (C.sub.3 -C.sub.6)cycloalkyl and phenyl,
- R.sub.3 is selected from the group consisting of hydrogen and halogen, X is selected from the group consisting of --O--, --S-- and --NR.sub.4 -- in which R.sub.4 is selected from the group consisting of hydrogen and (C.sub.1 -C.sub.4)alkyl.
A 2-(4-Hydroxyphenylthio)-3-isopropyl-1-methylindole.
3-(4-Hydroxyphenylthio)-2-isopropylindole.
Dependencies are inferred from the claim text.