Loading patent…
AssigneeLaboratorio Farmaceutico C.T. S.r.l.
InventorsMario Brufani, Antonella Loche, Vincenzo Perlini, Donato Pocar
Estimating the term…
Thiadiazole derivatives of general formula (I) ##STR1## wherein R.sub.1 is selected from the class consisting of: C.sub.1 -C.sub.10 linear or branched alkyl, benzyl, optionally substituted at the aromatic ring with one or more groups selected on their turn from the class consisting of : C.sub.1 -C.sub.20 linear or branched alkyl residues , nitro groups, halogen atoms, C.sub.1 -C.sub.20 linear or branched alkoxy, hydroxy and C.sub.2 -C.sub.20 linear or branched acyloxy groups, R.sub.2 is selected from H, C.sub.2 -C.sub.10 alkanoyl, cycloalkanoyl wherein this ring has from 3 to 10 carbon atoms, aroyl, and R.sub.3 is selected from H and C.sub.1 -C.sub.10 alkyl, for the treatment of depressive states and anxiety, a process for their preparation and relative pharmaceutical compositions containing them as the active ingredient.
A therapeutical method for the treatment of depressive states and anxiety, comprising administering an effective amount of a thiadiazole derivative of general formula (I) ##STR7## wherein R.sub.1 is selected from the group consisting of C.sub.1 -C.sub.10 linear or branched alkyl, benzyl, benzyl which is substituted on the aromatic ring with one or more groups selected from the group consisting of C.sub.1 -C.sub.20 linear or branched alkyl groups, nitro groups, halogen atoms, C.sub.1 -C.sub.20 linear or branched alkoxy groups, hydroxy and C.sub.2 -C.sub.10 linear or branched acyloxy groups, R.sub.2 is selected from the group consisting of H, C.sub.2 --C.sub.20 alkanoyl, cycloalkanoyl wherein the ring has from 3 to 10 carbon atoms, aroyl and R.sub.3 is selected from the group consisting of H and C.sub.1 -C.sub.10 alkyl.
A therapeutic method for the treatment of depressive states and anxiety comprising administering an affective amount of thiadiazole derivative of formula (I) ##STR8## wherein:
Dependencies are inferred from the claim text.