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US 5,401,774 AGranted
Method for treating patients with precancerous lesions by administering substituted sulfonyl idenyl acetic and propionic acids and esters to patients with lesions sensitive to such compounds
AssigneesUniversity of Arizona, FGN, Inc.
InventorsRifat Pamukcu, Klaus Brendel
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Abstract
Substituted indenyl sulfonyl acetic acids are useful in the treatment of precancerous lesions sensitive to treatment with those sulfonyl compounds.
Claims1
A method for treating a patient in need thereof with precancerous lesions sensitive to the compounds below, comprising administering to the patient a physiologically effective amount of a compound of the formula:
- ##STR3## wherein R.sub.1 is selected from the group consisting of hydrogen or lower alkyl;
- wherein R.sub.2 is lower alkyl;
- wherein R.sub.3 is a halogen;
- wherein R.sub.4 is hydrogen;
- wherein R.sub.5 is loweralkyl sulfonyl;
- and
- wherein M is hydroxy.
4 more elements
Dependencies are inferred from the claim text.