9-amino-1,4ethano-1,2,3,4-tetrahydroacridine and related compounds

A compound of the formula ##STR13## wherein R is hydrogen or loweralkyl;

• R.sub.1 is hydrogen, loweralkyl, aryl, diloweralkylaminoloweralkyl, arylloweralkyl, diarylloweralkyl, aryl(CH.sub.2).sub.m--O--(CH.sub.2).sub.1 -- or diarylCH(CH.sub.2).sub.k --O--(CH.sub.2).sub.1 --;
• wherein aryl is unsubstituted phenyl or phenyl substituted with 1, 2 or 3 substituents each of which being independently loweralkyl, loweralkoxy, halogen, hydroxy, trifluoromethyl, phenoxy or benzyloxy;
• m is 0, 1, 2, 3 or 4;
• 1is 2, 3, 4, or 5;
• k is 0, 1, 2, or 3;
• wherein the sum of m+1 is <6 and the sum of k+1 is <5;
• R.sub.2 and R.sub.3 are independently H or CH.sub.3 ;
• X is hydrogen, loweralkyl, cycloalkyl, loweralkoxy, halogen, hydroxy, nitro, trifluoromethyl, formyl, loweralkylcarbonyl, arylcarbonyl, --SH, loweralkylthio, --NHCOR.sub.4 or NR.sub.5 R.sub.6 where R.sub.4 is hydrogen or loweralkyl, and R.sub.5 and R.sub.6 are independently hydrogen, loweralkyl, and cycloalkyl;
• Y and Z are independently a direct bond, CR.sub.7 R.sub.8 or CR.sub.7 R.sub.8 --CR.sub.9 R.sub.10 ;
• and L and Q are independently CR'.sub.7 R'.sub.8, CR'.sub.7 R'.sub.8,--CR'.sub.9 R'.sub.10, CR'.sub.7 .dbd.CR'.sub.9 or C--R'.sub.7 R'.sub.8 --CR'.sub.9 R'.sub.10 --CR.sub.11 R.sub.2, where each of R.sub.7 through R.sub.12 and R'.sub.7 through R'.sub.10 is indepndently H or CH.sub.3 ;
• a stereo, optical and geometrical isomer thereof, and a pharmaceutically acceptable acid addition salt thereof.