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US 5,401,651 AGranted
DNA encoding ENA-78, a neutrophil activating factor
OwnerAlfred Walzinventor
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Abstract
The invention relates to a novel factor comprising a polypeptide denominated ENA-78, said factor being derived from epithelial cells and having the ability to activate neutrophils, as well as DNA coding for such factors, methods of treating neutrophil deficiencies, methods of identifying inhibitors of ENA-78 using a novel assay, the inhibitors identified by such an assay, and methods for treating acute and chronic lung disorders using such inhibitors.
Claims6
An isolated DNA sequence encoding a polypeptide consisting of amino acids 1-78 shown in SEQ ID NO:
- 12, said polypeptide having the ability to activate neutrophils.
An isolated DNA sequence encoding a polypeptide consisting of amino acids 1-72 shown in SEQ ID NO:
- 9, said polypeptide having the ability to activate neutrophils.
Dependencies are inferred from the claim text.