Intravenous infusion of pharmaceuticals

A system for the intravenous infusion of pharmaceuticals, comprising:

• a syringe assembly prefilled with a pharmaceutical preparation requiring dilution, dissolution or suspension in a liquid medium prior to administration, the assembly comprising an elongated body, a piston movable longitudinally within and in sealing engagement with the body, a plunger for insertion into one end of the body to move the piston, a penetrable closure at the other end of the body, and a connector assembly for establishing a passage for liquid between the interior of the body and a liquid conduit, the connector assembly comprising first and second cannula means projectable through said penetrable closure, means for establishing connection between the first cannula means and the liquid conduit, an air valve establishing a controlled connection to the exterior of the connector assembly, and means establishing connection between the second cannula means and the air valve;
• and
• a flexible tube for connection to a Y-connector in an intravenous drip assembly through which diluent fluid may flow from the drip assembly through the connector assembly to the syringe body, and through which diluted, dissolved or suspended pharmaceutical may pass from the syringe body to the Y-connector.