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US 5,399,737 AGranted
Quaternary ammonium siloxane compounds and methods for their use
AssigneeAlcon Laboratories, Inc.
InventorsJoonsup Park, Joseph J. Falcetta
Life of this patent
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Abstract
Novel quaternary ammonium siloxane compounds and methods for their use are disclosed.
Claims11
Compounds of the structure:
- ##STR22## wherein:
- and Y are C.sub.1 -C.sub.5 alkyl, phenyl, or W groups, wherein W has the structure:
- ##STR23## and Z is C.sub.1 -C.sub.5 alkyl or phenyl and n is an integer from zero to five;
- and
- R, R', R" are the same or different and are C.sub.1 -C.sub.20 alkyl, benzyl or substituted benzyl, aromatic and substituted aromatic, cycloalkyl or substituted cycloalkyl;
- and D.sup.- is an anion.
3 more elements
Compounds of the structure:
- ##STR24## wherein:
- X and Y are C.sub.1 -C.sub.5 alkyl, phenyl, or W, wherein W has the structure:
- ##STR25## and Z is C.sub.1 -C.sub.5 alkyl and phenyl and n is an integer from zero to five;
- and
- R, R', R" are the same or different radicals and are C.sub.1 -C.sub.20 alkyl, benzyl, or substituted benzyl, aromatic or substituted aromatic, cycloalkyl, or substituted cycloalkyl;
- or R, R' and R" are the same or different and are C.sub.1 -C.sub.20 aliphatic hydrophilic radicals;
- and D.sup.- is an anion.
4 more elements
A compound with the structure:
- ##STR26##
Compounds of the structure:
- ##STR27## wherein:
- A and A' are the same or different and have the structure:
- ##STR28## wherein:
- X and Y are C.sub.1 -C.sub.5 alkyl, phenyl, or W;
- wherein W has the structure:
- ##STR29## and Z is C.sub.1 -C.sub.5 alkyl or phenyl and n is an integer from zero to five;
- R, R', R", R'", are the same or different and are C.sub.1 -C.sub.20 alkyl, benzyl, or substituted benzyl, aromatic, or substituted aromatic, or cycloalkyl or substituted cycloalkyl;
- Q is a radical of linear or branched C.sub.2 -C.sub.20 alkyl, unsaturated C.sub.3 -C.sub.20 alkyl, C.sub.2 -C.sub.20 alkyloxy, aryl or alkyl aryl substituted or unsubstituted, cycloalkyl or substituted cycloalkyl, or a heteroalkyl structure in which the quaternary ammonium atom may or may not be part of the heteroalkyl structure;
- and D.sup.- is an anion.
6 more elements
Compounds of the structure:
- ##STR30## wherein:
- X and Y are C.sub.1 -C.sub.5 alkyl, phenyl, or W, wherein W has the structure:
- ##STR31## and Z is C.sub.1 -C.sub.5 alkyl or phenyl and n is an integer from zero to five;
- R, R' are the same or different and are C.sub.1 -C.sub.20 alkyl, benzyl or substituted benzyl, aromatic or substituted aromatic, or cycloalkyl;
- Q is alkyl, aryl or cycloalkyl having a polymerizable vinyl group;
- and
- D.sup.-1 is an anion.
4 more elements
Compounds of the structure:
- ##STR32## wherein:
- R is alkyl, aryl or cyloalkyl having a polymerizable vinyl group;
- X and Y are C.sub.1 -C.sub.5 alkyl, phenyl, or W wherein W has the structure:
- ##STR33## wherein Z is C.sub.1 -C.sub.5 alkyl or phenyl and g is an integer from zero to five;
- Q is alklyl, aryl or cycloalkyl having a polymerizable and a water compatible functional group;
- D.sup.- is a pharmaceutically acceptable anion;
- and
- m and n are the ratio of the two monomers.
5 more elements
A compound having the structure:
- ##STR34## wherein:
- m is 1 and n is 1.
A compound having the structure:
- ##STR35## wherein:
- m is 1 and n is 0.
Dependencies are inferred from the claim text.