Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate
AssigneeEli Lilly and Company
InventorsWilliam C. Henning, Michael E. O'Dea
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Abstract
The invention is directed to the crystalline isopropyl alcohol solvate of loracarbef, and also is directed to a process for the preparation of the crystalline monohydrate form of the compound of formula (I) ##STR1## which includes exposing the crystalline isopropyl solvate form of the compound of formula (I) to a temperature of between about 50.degree. and 90.degree. C. and a relative humidity of between about 60 to about 100%.
Claims3
A process for the preparation of the crystalline monohydrate form of the compound of formula (I) ##STR5## which comprises exposing the crystalline isopropanolate form of the compound of formula (I) to a temperature of between about 50.degree. to about 90.degree. C. and a relative humidity of between about 60 to about 100%.
Dependencies are inferred from the claim text.