Chlormethiazole in the treatment of neurodegeneration
AssigneeAktiebolaget Astra
InventorsAlfred R. Green, Alan J. Cross, Bernard R. Boar
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Abstract
A thiazole of the following formula is disclosed ##STR1## for the treatment of neurodegeneration involving loss of neuronal structure.
Claims7
A method for the treatment of neurodegeneration involving loss of neuronal structure following a pathological insult in the brain of a human subject comprising administering to said subject a therapeutically effective amount of 5-(2-chloroethyl)-4-methylthiazole, or a pharmaceutically acceptable salt or solvate thereof.
A method for the treatment of neurodegeneration involving loss of neuronal structure following a pathological insult in the brain of a human subject caused by stroke, cerebral ischemia, hypoxia, or multi-infarct dementia, comprising administering to said subject a therapeutically effective amount of 5-(2-chloroethyl)-4-methylthiazole or a pharmaceutically acceptable salt or solvate thereof, in the dosage range of about 10-1000 mg/kg body weight, in combination with a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.