Methods and compositions for diagnosing cat scratch disease and bacillary angiomatosis caused by Rochalimaea henselae
AssigneeUnited States of America
InventorsRussell L. Regnery, Burt E. Anderson
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Abstract
The present invention relates to a method of diagnosing cat scratch disease and a method of diagnosing bacillary angiomatosis in a subject by detecting the presence of Rochalimaea henselae or an immunogenically specific determinant thereof in the subject. Also provided by the present invention is a vaccine comprising an immunogenic amount of a nonpathogenic Rochalimaea henselae or an immunogenically specific determinant thereof and a pharmaceutically acceptable carrier.
Claims17
A method of diagnosing cat scratch disease or the previous existence of cat scratch disease in a subject, comprising detecting the presence of Rochalimaea henselae in the subject, and correlating the presence of Rochalimaea henselae with the presence of cat scratch disease in the subject.
A method of diagnosing bacillary angiomatosis or the previous existence of bacillary angiomatosis in a subject comprising detecting the presence of Rochalimaea henselae, and correlating the presence of Rochalimaea henselae with the presence of bacillary angiomatosis in the subject.
A purified antibody or antigen-binding fragment thereof that specifically binds with Rochalimaea henselae.
Dependencies are inferred from the claim text.