Test element for optically testing biological fluids in clinical diagnostic applications
AssigneeEastman Kodak Company
InventorsGustavo R. Paz-Pujalt, Charles R. Moon
Life of this patent
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Abstract
An integral test element for analysis of liquids comprising: a) a spreading layer for uniformly spreading within itself at least a substance of a liquid sample applied to the element; b) a reagent layer in fluid contact with the spreading layer and permeable to a substance spreadable within the spreading layer or to a reaction product of such a substance, the reagent layer having a chemically interactive material which, in the presence of the substance or of the reaction product of the substance, produces a detectable change in the element; and c) a radiation upconversion phosphor layer or crystal for producing an upconverted radiation when excited by visible or infrared excitation radiation from an independent source.
Claims7
An integral test element for determination of an analyte in a liquid comprising:
- a) a spreading layer for uniformly spreading within itself at least a portion of a liquid sample applied to the element;
- b) a reagent layer in fluid contact with said spreading layer and permeable to said analyte spreadable within said spreading layer or to a reaction product of said analyte, said reagent layer having a chemically interactive material which, in the presence of said analyte or of said reaction product of the analyte, produces a detectable change in the element;
- and
- c) a radiation upconversion phosphor layer or crystal for producing upconverted radiation when excited by visible or infrared excitation radiation from an independent source, wherein said upconverted radiation interacts with said sample or analyte, absorbing a characteristic radiation wavelength (.lambda.) in a manner proportional to the concentration of the analyte in the liquid.
Dependencies are inferred from the claim text.