Treatment of ocular hypertension with an ocular synergistic combination
AssigneeR-Tech Ueno, Ltd.
InventorRyuji Ueno
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Abstract
A method for treatment of ocular hypertension which comprises ocularly administering, to a subject in need of such treatment, a oculo-hypotensively synergistic combination of (a) a 13,14-dihydro-15-ketoprostaglandin compound, and (b) a cholinergic agent in an amount effective in treatment of ocular hypertension.
Claims12
A method for treatment of ocular hypertension which comprises ocularly administering, to a subject in need of such treatment, an oculo-hypotensively synergistic combination of
- (a) a 13,14-dihydro-15-ketoprostaglandin compound, and
- (b) pilocarpine or a pharmaceutically acceptable salt thereof,
- in an amount effective in treatment of ocular hypertension.
A pharmaceutical composition for treatment of ocular hypertension comprising an oculo-hypotensively synergistic combination of
- (a) a 13,14-dihydro-15-ketoprostaglandin compound, and
- (b) pilocarpine or a pharmaceutically acceptable salt thereof,
- in association with a pharmaceutically acceptable carrier, diluent or excipient, in which the components (a) and (b) are present in a ratio (a):(b) of 1:10 to 1:2,000.
A pharmaceutical composition for treatment of ocular hypertension comprising an oculo-hypotensively synergistic combination of
- (a) 0.005 to 2% by weight of a 13,14-dihydro-15-ketoprostaglandin compound, and
- (b) 0.005 to 20% by weight of pilocarpine or a pharmaceutically acceptable salt thereof useful in treating glaucoma or ocular hypertension
- in association with a pharmaceutically acceptable carrier, diluent or excipient.
A method for treatment of ocular hypertension which comprises ocularly administering, to a subject in need of such treatment, an oculo-hypotensively synergistic combination of
- (a) a 13,14-dihydro-15-ketoprostaglandin F compound, and
- (b) pilocarpine or a pharmaceutically acceptable salt thereof useful in treating glaucoma or ocular hypertension
- in an amount effective in treatment of ocular hypertension.
A method for treatment of ocular hypertension which comprises ocularly administering, to a subject in need of such treatment, an oculo-hypotensively synergistic combination of
- (a) a 13,14-dihydro-15-keto-20-loweralkyl-prostaglandin F compound, and
- (b) Pilocarpine or, if appropriate, pharmaceutically acceptable salt thereof in an amount effective in treatment of ocular hypertension.
Dependencies are inferred from the claim text.