2,4-dioxoimidazolidine compounds and compositions, and processes for administering same

Compound of the formula I ##STR18## in which Y denotes --(CH.sub.2).sub.m --CO--, where m represents an integer from 1 to 4, or ##STR19## R.sup.1 denotes --(CH.sub.2).sub.n --NH--X, where n represents an integer from 1 to 6, --(CH.sub.2).sub.p --C.sub.6 H.sub.4 --NH--X, --(CH.sub.2).sub.p --C.sub.6 H.sub.4 --C(.dbd.NH)--NH.sub.2 or --(CH.sub.2).sub.p --C.sub.6 H.sub.4 --CH.sub.2 --NH--X, where p in each case represents 1 or 2, or where ##STR20## is replaced by ##STR21## X.sup.1 denotes --NHX, --CH.sub.2 NHX or --C(=NH)--NH.sub.2 ;

• X denotes hydrogen, (C.sub.1 -C.sub.6)-alkyl or a radical of the formula II ##STR22## where R' and R" independently of one another represent hydrogen or (C.sub.1 -C.sub.6)-alkyl;
• R.sup.2 denotes hydrogen or (C.sub.1 -C.sub.6)-alkyl;
• R.sup.3 denotes hydrogen or phenyl;
• R.sup.4 denotes --COOR.sup.5, --CO--N (CH.sub.3)--R.sup.5 or --CO--NH--R.sup.5 ;
• R.sup.5 denotes (C.sub.1 -C.sub.8)-alkyl which is substituted
• a) by amino-(C.sub.2 -C.sub.14)-alkylaminocarbonyl, where the alkyl radical is unsubstituted or is substituted by hydroxyl, amino, mercapto, (C.sub.1-C.sub.8)-alkoxy, phenyl or phenyl-(C.sub.1 -C.sub.4)-alkyl, and which
• b) is additionally substituted by from zero to two identical or different radicals selected from the group consisting of hydroxyl, hydroxycarbonyl, aminocarbonyl, amino, mercapto, (C.sub.1 -C.sub.8)-alkoxy, (C.sub.1 -C.sub.8)-alkoxycarbonyl, phenyl-(C.sub.1 -C.sub.3)-alkoxycarbonyl, (C.sub.3 -C.sub.8)-cycloalkyl and a radical R.sup.6 ;
• R.sup.6 denotes phenyl, phenyl-(C.sub.1 -C.sub.4)-alkyl or denotes a radical R.sup.7, where the phenyl radical is unsubstituted or is substituted by one or more identical or different radicals selected from the group consisting of (C.sub.1 -C.sub.8)-alkyl, (C.sub.1 -C.sub.8)-alkoxy, halogen, nitro and trifluoro-methyl;
• R.sup.7 denotes --NR.sup.8 R.sup.9, --OR.sup.8, --SR.sup.8, an amino acid side chain, a natural or unnatural amino acid radical, imino acid radical or dipeptide radical or an ester or amide thereof, or denotes a radical --COR.sup.7', in which R.sup.7' is defined as R.sup.7 ;
• R.sup.8 denotes hydrogen, (C.sub.2 -C.sub.8)-alkyl, phenyl-(C.sub.1 -C.sub.4)-alkyl, (C.sub.1 -C.sub.8)-alkylcarbonyl, (C.sub.1 -C.sub.8)-alkoxycarbonyl, phenylcarbonyl, phenyl-(C.sub.1 -C.sub.4)-alkylcarbonyl, or phenyl-C.sub.1 -C.sub.4)-alkoxycarbonyl;
• R.sup.9 denotes hydrogen, (C.sub.1 -C.sub.8)-alkyl, phenyl or phenyl-(C.sub.1 -C.sub.4)-alkyl;
• or their physiologically tolerable salts.