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US 5,397,783 AGranted
3-aminochroman spiro compounds
AssigneeAdir et Compagnie
InventorsGerald Guillaumet, Tchao Podona, Gerard Adam, Beatrice Guardiola, Pierre Renard
Life of this patent
Estimating the term…
Abstract
The invention relates to a compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3, A and m are as defined in the description. Medicinal product which is useful for treating depression and anxiety.
Claims6
A spirochroman compound selected from those of formula (I):
- ##STR95## in which:
- m is 1,
- A denotes methylene (CH.sub.2)
- R.sub.1 denotes:
- (I) hydrogen,
- or (II) linear or branched alkyl having 1 to 6 carbon atoms, inclusive,
- R.sub.2 denotes --O--(II) substituted by any one of the following groups:
- ##STR96## in which:
- n is 1,
- R.sub.3 denotes hydrogen
- their optical isomers, isolated or in mixture form,
- and pharmaceutically-acceptable inorganic or organic acid addition salts thereof.
9 more elements
A compound which is spiro[{5-[4-(3-azabicyclo-[3.3.0]octane-2,4-dione-3-yl)-n-but-1-yl]oxychro man}-3,2'-(N-propylpyrrolidine)] or a pharmaceutically-acceptable acid addition salt thereof.
Dependencies are inferred from the claim text.