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US 5,397,710 AGranted
Process for measuring magnesium in biological fluids
AssigneeDavid Diagnostics, Inc.
InventorGary D. Steinman
Life of this patent
Estimating the term…
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AssigneeDavid Diagnostics, Inc.
InventorGary D. Steinman
Estimating the term…
A process for rapidly and conveniently measuring the magnesium concentration of a biological fluid, such as blood or urine, is carried out by fixing amounts of a chelatometric dye, metal cation masking agents, a chelating agent, an alkaline buffer, and a stabilizer on a bibulous material covered with a semipermeable membrane, adding the test specimen, and measuring the amount of color change of the dye at a selected wavelength. The amount of color change is proportional to the quantity of magnesium in the original specimen and can be measured by visual comparison to a standard color chart or with a dedicated reflectance photometer. Furthermore, a method is given for expanding the range of linearity. The method for making the dry indicator includes coating bibulous material with a reaction solution which is dried thereon, followed by coating this material with an organic solution which is dried thereon. The dry indicator composition includes a dihydroxy complexometric dye, a masking agent, a stabilizer, an alkaline buffer, a chelating agent, and a bibulous material.
A process for measuring the magnesium concentration of a biological fluid test sample with a dry indicator bibulous material, comprising the steps of:
A process for making a bibulous material dry indicator composition for measuring the magnesium concentration of a biological fluid in a dry chemistry procedure, comprising the steps of:
A dry indicator composition capable of exhibiting a sufficient color transition upon contracting a biological fluid test sample to demonstrate the presence or concentration of magnesium ions in the test sample comprising the components:
Dependencies are inferred from the claim text.