Resorbable materials based on independently gelling polymers of a single enantiomeric lactide
AssigneeBoard of Regents, The University of Texas System
InventorsAllan G. A. Coombes, James D. Heckman, Barbara D. Boyan
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Abstract
Resorbable materials and their preparation based on gelling a solution of a single polylactide enantiomer. The gel may be dried to produce solid materials, or may be extracted with a nonsolvent prior to drying to make microporous materials. Physical and mechanical properties of the material may be varied by varying the molecular weight of the gelling polymer, or by blending the gelling solution with other polymers or fillers. The resorbable materials can be used to make biodegradable implantation devices.
Claims19
A resorable implantation device comprising a dried gel, the dried gel being formed from cooling a polymer solution comprising an independently-gelling polymer of a single enantiomeric lactide dissolved in a solvent to form a gel capable of substantially retaining a molded shape upon handling thereof, and drying the gel to form the resorbable implantation device.
A resorbable implantation device comprising a dried microporous material, the dried microporous material being formed from cooling a polymer solution comprising an independently-gelling polymer of a single enantiomeric lactide dissolved in a solvent to form a gel capable of substantially retaining a molded shape upon handling thereof, extracting the solvent with a nonsolvent to precipitate out the microporous material, and drying the microporous material to form the resorbable implantation device.
Dependencies are inferred from the claim text.