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US 5,397,564 AGranted
Aerosol preparation for external use
AssigneeTaisho Pharmaceutical Co., Ltd.
InventorsToshimitsu Seki, Kingo Narumi, Tatsuoki Iguchi, Shozo Kouchiwa
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Abstract
This invention provides an aerosol preparation for topical use, primarily for skin cooling, which is novel in that it is propelled out in the form of a sherbet-like foam. The concentrate is based on water and a lower alcohol and a liquefied. petroleum gases and dimethyl ether is used as a propellant. By using the basic agent and the propellant in a specified ratio, a sherbet-like foam can be formed. The aerosol preparation may also incorporate a drug.
Claims1
A sherbet, foam forming aerosol preparation for topical use comprising:
- (A) a propellant selected from the group consisting of liquefied petroleum gas, dimethyl ether and mixtures thereof, said propellant having a vapor pressure of 2 to 5 kg/cm.sup.2 at 20.degree. C., and
- (B) water, or a mixture of water and not more than its weight of a lower alcohol having 1-4 carbon atoms and a nonionic surface-active agent,
- the weight ratio of (A):(B) being from 90:10 to 60:40.
Dependencies are inferred from the claim text.