7-(4-[4-aminophenyl)sulphonyl]-1-piperazinyl fluorquinolonic derivatives and synthesis
OwnerRuben H. Manzo, Daniel A. Allemandi +1inventors
InventorsRuben H. Manzo, Daniel A. Allemandi, Jorge D. Perez
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Abstract
The present invention relates to novel compounds of 7-(4-[4-aminophenyl)sulphonyl]-1-piperazinyl) fluorquinolonic derivatives, of the formula: ##STR1## wherein R.sub.1 represents C.sub.1 -C.sub.3 alkyl, and are denominated N-sulphanilyl-derivatives. They are obtained by the process of the invention from the 7-(1-piperazinyl) fluorquinolonic compounds and their esters.
Claims2
A 7-(4-[4-aminophenyl)sulphonyl]-1-piperazinyl) fluorquinolonic derivative, having the formula:
- ##STR6## wherein R.sub.1 represents C.sub.1 -C.sub.6 alkyl.
A process for preparing 7-(4-[4-aminophenyl)sulphonyl]-1-piperazinyl) fluorquinolonic derivatives comprising:
- reacting 7-(1-piperazinyl) fluorquinolone or an ester thereof with N-acetylsulphanilyl chloride and hydrolyzing the ester and recovering the derivative.
Dependencies are inferred from the claim text.