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US 5,395,848 AGranted
Methods of treating hyperlipidemia with substituted azaspiranes
AssigneeSmithKline Beecham Corporation
InventorsPeter J. Bugelski, Wiliam D. Kerns
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Abstract
This invention discloses a method of treating hyperlipidemia in a mammal by administering an effective amount of a substituted azaspirane.
Claims13
A method of treating hyperlipidemia in a mammal comprising administering to said mammal a therapeutically effective amount of a compound of the formula ##STR3## wherein:
- n is 3-7;
- m is 1 or 2;
- R.sup.1 and R.sup.2 are the same or different and are selected from hydrogen or straight or branched chain alkyl, provided that the total number of carbon atoms contained by R.sup.1 and R.sup.2 when taken together is 5-10;
- or R.sup.1 and R.sup.2 together form a cyclic alkyl group having 3-7 carbon atoms;
- R.sup.3 and R.sup.4 are the same or different and are selected from hydrogen or straight chain alkyl having 1-3 carbon atoms;
- or R.sup.3 and R.sup.4 are joined together with the nitrogen to form a heterocyclic group having 5-8 atoms;
- or a pharmaceutically acceptable salt or hydrate or solvate thereof.
4 more elements
Dependencies are inferred from the claim text.