Pyridones

A compound selected from the group consisting of all possible racemic, enantiomeric and diastereoisomeric forms of a compound of the formula ##STR79## wherein E and G together form a group selected from the group consisting of a) ##STR80## R is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms, alkenyl or alkynyl of 2 to 6 carbon atoms optionally substituted with carbocyclic aryl selected from the group consisting of phenyl, naphthyl and indenyl optionally substituted with at least one member of the group consisting of --OH, --CF.sub.3, alkoxy of 1 to 6 carbon atoms, --NO.sub.2, --CN, --NH.sub.2, free and esterified carboxy, acyl of 1 to 7 carbon atoms selected from the group consisting of formyl, acetyl, propionyl or benzoyl, alkoxy of 1 to 6 carbon atoms, --OH, --NH.sub.2, alkylamino and dialkylamino of 1 to 6 carbon atoms, acyloxy selected from the group consisting of formyloxy, acetyloxy, propionloxy and benzoyloxy, --CN, carbamoyl and halogen, Y is selected from the group consisting of carbocyclic aryl selected from the group consisting of phenyl, naphthyl and indenyl, all optionally substituted with at least one substituted selected from the group consisting of halogen, hydroxy, alkyl, alkynyl and alkenyl of up to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, halo alkylthio of 1 to 6 carbon atoms, mono or dialkylamino of 1 to 6 carbon atoms, optionally esterified carboxy, haloalkyl of 1 to 6 carbon atoms, haloalkoxy of 1 to 6 carbon atoms, lower alkanoyl of up to 7 carbon atoms, lower alkanoylamido, alkoxy of 1 to 6 carbon atoms, alkylthio of 1 to 6 carbon atoms, carbamoyl and phenyl, benzoyl, A is a cycloalkylene of 3 to 6 carbon atoms optionally substituted with at least one substituent selected from the group consisting halogen, hydroxy, alkyl and alkenyl of up to 6 carbon atoms, phenyl, naphthyl, benzyl, phenethyl, cycloalkyl of 3 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, methoxymethyl, 1-ethoxy ethyl, phenoxy, benzyloxy, mercapto, alkylthio of 1 to 6 carbon atoms, carbocyclic arylthio, carbocyclic aralkylthio, amino, aminoethyl, mono or dialkylamino of 1 to 6 carbon atoms, nitro, cyano, azido, optionally esterified carboxy, formyl, acetyl, propionyl, benzoyl, acetoxy, propionyloxy, phthalimido, acetamido, benzamido, alkoxycarboxylamino of 2 to 6 carbon atoms, benzyloxycarbonylamino, R.sub.1 and R.sub.2 together with the nitrogen to which they are attached form pyrrolidino or piperidino optionally substituted with at least one substituent selected from the group consisting of phenyl, benzyl, alkoxy of 1 to 6 carbon atoms and alkyl of 1 to 6 carbon atoms and their non-toxic, pharmaceutically acceptable salts with acids and bases.