Fertility regulation with transforming growth factor .beta.
AssigneesYale University, The Trustees of the University of Pennsylvania
InventorsRonald F. Feinberg, Harvey J. Kliman
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Abstract
Therapeutic and diagnostic methods of use for the growth factor transforming growth factor .beta., are provided by this invention. In accordance with preferred embodiments, methods of determining and improving competence of a conceptus toward uterine implantation are provided as are methods for determining female infertility in mammals.
Claims5
A method of increasing the success rate of assisted implantation comprising administering transforming growth factor .beta. to an ovum or conceptus prior to introduction of said ovum or conceptus into the reproductive tract of a female mammal.
A method of increasing the success rate of assisted implantation comprising administering transforming growth factor .beta. to the reproductive tract of a female mammal prior to introduction of ovum, sperm or conceptus into the reproductive tract of a female mammal.
A method of increasing the success rate of assisted implantation comprising administering transforming growth factor .beta. simultaneously with introduction of ovum, sperm or conceptus into the reproductive tract of a female mammal.
A method of increasing the success rate of assisted implantation comprising administering transforming growth factor .beta. following introduction of ovum, sperm or conceptus into the reproductive tract of a female mammal.
Dependencies are inferred from the claim text.