Biodegradable microcapsules having walls composed of crosslinked atelocollagen and polyholoside
AssigneeColetica
InventorsAlain Huc, Marie-Christine Levy, Chantal Buffevant, Marie-Christine Andry
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AssigneeColetica
InventorsAlain Huc, Marie-Christine Levy, Chantal Buffevant, Marie-Christine Andry
Estimating the term…
The invention relates to microcapsules with a mixed wall of crosslinked atelocollagen and polyholosides, for example glycosaminoglycans, and to processes for the manufacture of the said microcapsules. According to the invention, the microcapsules comprise a mixed wall of crosslinked atelocollagen and polyholosides, for example glycosaminoglycans, the proportion of polyholosides, for example glycosaminoglycans, relative to the atelocollagen preferably being between 18 and 50% by weight. These microcapsules can be manufactured either by a process involving interfacial crosslinking or by the extrusion of a laminar flow which is broken up by vibrations into individual droplets, which fall into a crosslinking bath. These microcapsules are biocompatible by virtue of the presence of atelocollagen, which has most of the advantageous properties of collagen, namely a very low antigenicity and a perfect biodegradability. They are therefore particularly suitable for the manufacture of cosmetic, pharmaceutical or food compositions.
A microcapsule comprising a cross-linked outer wall surrounding a filled inner space, said outer wall resulting from crosslinking between molecules of atelocollagen and polyholoside.
A microcapsule comprising a cross-linked outer wall surrounding a filled inner space and further comprising an active compound, said outer wall resulting from crosslinking between molecules of atelocollagen and polyholoside.
A microcapsule comprising a crosslinked outer wall surrounding a filled inner space, said filled inner space comprising a mixture of atelocollagen and polyholoside, said outer wall resulting from crosslinking between molecules of said atelocollagen and said polyholoside.
A microcapsule comprising a crosslinked outer wall surrounding a filled inner space, said filled inner space comprising a mixture of atelocollagen, polyholoside, and active compound, said active compound being selected from the group consisting of cosmetic, pharmaceutical and food compounds, and said outer wall resulting from crosslinking between molecules of said atelocollagen and said polyholoside.
A microcapsule comprising a cross-linked outer wall surrounding an inner space, said outer wall resulting from crosslinking between molecules of atelocollagen and polyholoside, said inner space comprising an encapsulated oily phase.
A microcapsule comprising a cross-linked outer wall surrounding an inner space and further comprising an active compound, said outer wall resulting from crosslinking between molecules of atelocollagen and polyholoside, said inner space comprising an encapsulated oily phase.
Dependencies are inferred from the claim text.