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AssigneeTerumo Kabushiki Kaisha
InventorsMikio Koide, Jun Konishi, Kazuhito Ikegami, Ken-ichi Osaki
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Wound-covering materials comprising two layers, a first support layer which is to be in contact with a wound and a second moisture permeation-controlling layer which may optionally contain an antimicrobial agent are taught. The support layer is formed from a biocompatible highly aqueous gel-forming substance, e.g., carboxymethylcelluloses, alginates, hyaluronates, poly(meth)acrylates, chitosan derivatives and chitin derivatives, and at least a portion of the support layer which is to be in contact with a wound is coated with a water-repellant substance, e.g., silicones, polyurethanes, styrene-butadiene-styrene block copolymers and polytetrafluoroethylenes. The moisture permeation controlling layer may, e.g., be formed from steam permeable resin films made of silicone or polyurethane elastomers. The resultant wound-covering materials inhibit infection and pain, maintain adequate water retention, and do not produce bioincompatibility responses when applied to the site of wounds.
A wound-covering material comprising (a) a support layer formed of a film of a biocompatible highly aqueous gel-forming substance, wherein at least a portion of the support layer which is to be in contact with a wound includes a coating of a water-repellent substance selected from the group consisting of silicones, polyurethanes, styrene-butadiene-styrene block copolymers, and polytetrafluoroethylenes, said coating surrounding the film of said support layer, and (b) a moisture permeation-controlling layer which is attached on and in contact with said support layer on the side opposite to the portion of the support layer which is to be contacted with a wound, wherein said moisture permeation-controlling layer is a porous membrane comprised of either polyolefin or halogenated polyolefin and the surface of said porous membrane which is opposite to the surface of said porous membrane which is in contact with said support layer is coated with a hydrophilic polymer by means of chemical bonding, and optionally, (c) either or both of said layers containing an antimicrobial agent.
Dependencies are inferred from the claim text.