# US 5,394,457 A · Device for marking body sites for medical examinations > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 5,394,457 A - Document ID: US5394457A - Status: Granted - Kind: A - Application number: 08/133,675 - Filed: 1993-10-07 - Granted: 1995-02-28 - Earliest claimed: 1992-10-08 - Assignees: Leibinger GmbH - Inventors: Karl Leibinger; Franz Leibinger; Stephan Felber; Clemens Plangger - Web page: https://patentgrep.com/patent/US5394457A ## CPC - A61B 6/583: {using calibration phantoms} - A61B 6/12: Arrangements for detecting or locating foreign bodies - A61B 90/39: {Markers, e.g. radio-opaque or breast lesions markers} - A61B 90/10: for stereotaxic surgery, e.g. frame-based stereotaxis - A61B 2090/363: {Use of fiducial points} - A61B 2090/3916: {Bone tissue} - A61B 2090/3995: {Multi-modality markers} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract A device for marking body sites for imaging medical examinations, such as nuclear spin resonance tomography (NMR), computed tomography (CT), roentgen ray analysis (X-ray), or positron emission tomography (PET), comprises fixtures (10) which are adapted to be fastened to the body and/or to a stereotaxic means or a mask arrangement. Markers (18) containing a substance (20) which provides sharp contrast in the generation of images are adapted to be slid selectively into those fixtures. The fixtures are made of a material which does not disturb the imaging, with at least two different imaging examination procedures. ## Claims ### Claim 1 A device for marking body sites for imaging medical examination procedures comprising: fixtures made of a material that does not disturb the imaging with at least two different imaging examination procedures and adapted to be fastened either to the body or to a stereotaxic means; markers releasably fastened to the fixtures and including a substance which is contrasty in imaging; and at least two different markers to be attached to a fixture, each in a predetermined position and each having a contrasty substance for different imaging examination procedures. ### Claim 2 (depends on 1) A device as in claim 1 wherein said fixtures adapted to be fastened to a stereotaxic means further includes: an elongated structure having an upper portion and a lower portion, said upper portion having a larger diameter than said lower portion; and said lower portion including clamping means for fastening said fixtures to said stereotaxic means. ### Claim 3 (depends on 2) A device as in claim 2 wherein said clamping means of said lower portion of said fixture engages a bore in said stereotaxic means and further comprises: first and second spreader wings separated by a slot forming said lower portion, said lower portion adapted to be fastened to said stereotaxic means by insertion of said lower portion in said bore provided in said stereotaxic means until the larger diameter of said upper portion abuts said bore; and said spreader wings providing said clamping effect in said bore in said stereotaxic means. ### Claim 4 (depends on 3) A device as in claim 3 wherein said fixture further includes an elongated recess in said elongated portion of said fixture for receiving one of said markers. ### Claim 5 (depends on 1) A device as in claim 1 wherein said fixture adapted to be fastened to the body further includes: an elongated structure having a first orifice of a first diameter extending partially therein for receiving said marker; and a second orifice of smaller diameter extending from the termination of said first orifice through the remainder of said elongated structure, said second orifice enabling a bone screw to be inserted therein for attaching said fixture to said body. ### Claim 6 (depends on 1) A device as in claim 1 wherein said fixture adapted to be fastened to the body further comprises: an elongated structure having an upper portion and a lower portion; said upper portion including an orifice therein for releasably receiving said marker; said lower portion having a threaded orifice therein for attachment to a bone screw previously attached to the body; and a slot in said upper portion for enabling the use of a screwdriver to attach said fixture to said bone screw. ### Claim 7 (depends on 1) A device as in claim 1 wherein said fixture adapted to be fastened to said body further comprises: a substantially bell-shaped body having an orifice therein for receiving said fixture; and a plate larger than said bell-shaped body and attached to said bell-shaped body for attachment to the skin of a body. ### Claim 8 (depends on 7) A device as in claim 7 wherein said plate is adhesively attached to the skin of said body. ### Claim 9 (depends on 1) A device as in claim 1 further including a bore in said fixture for receiving said marker. ### Claim 10 (depends on 9) A device as in claim 9 wherein said marker includes: an upper portion and a lower portion; said lower portion being elongated for insertion in said bore in said fixture; and said upper portion including a cavity for receiving a contrasty substance for said imaging medical examination procedure. ### Claim 11 (depends on 10) A device as in claim 10 further including an orifice in said upper portion extending into said cavity to enable said contrasty substance to be inserted therein. ### Claim 12 (depends on 11) A device as in claim 11 wherein said orifice extending into said cavity is designed such that surface tension of said contrasty substance will prevent said contrasty substance from leaking out of said cavity. ### Claim 13 (depends on 11) A device as in claim 11 further including an elongated slot extending partially into said lower portion of said marker to form first and second spaced spreader wings to create a clamping effect when inserted in said bore of said fixture. ### Claim 14 (depends on 10) A device as in claim 10 wherein said marker further includes: a cap removably attached to said upper portion of said marker such that, when removed, said contrasty substance can be placed in said cavity; and when said cavity is filled with said contrasty substance, said cap may be replaced to seal said contrasty substance in said cavity. ### Claim 15 (depends on 14) A device as in claim 14 wherein: said cap is threadedly attached to said marker upper portion; said cavity is spherical in shape; and a hemispherical recess is formed in said cap and said marker upper portion to complement each other and form said spherical cavity when said cap is threadedly attached to said marker upper portion. ### Claim 16 (depends on 10) A device as in claim 10 wherein said upper portion of said marker includes: an arm-like transverse body extending transversely of said lower portion; a plurality of spaced cavities in said transverse body, each cavity receiving contrasty substances; and access means for each cavity in said transverse body for inserting said contrasty substance. ### Claim 17 (depends on 10) A device as in claim 10 wherein said upper portion of said marker includes: a vertically extending portion integrally formed with said lower portion; a plurality of spaced-through cavities extending transversely through said vertically extending portion; and inserts slidably mounted in at least one of said cavities, each insert having a hollow portion containing a particular contrasty substance such that different contrast media can be used at selected spacings from each other. ### Claim 18 (depends on 17) A device as in claim 17 wherein: the longitudinal centers of said cavities lie vertically along the longitudinal axis of said vertically extending portion of said marker; and the longitudinal centers of said inserts, when in said cavities, all lie vertically along the same axis. ### Claim 19 (depends on 18) A device as in claim 18 wherein said inserts comprise: an elongated cylindrical hollow body; and first and second hollow rods partially and removably inserted in corresponding ends of said hollow cylindrical body so as to form a cavity between said first and second rods in which said contrasty substance may be received. ### Claim 20 (depends on 17) A device as in claim 17 wherein: said transversely extending cavities in said upper portion are of different sizes; and said inserts are of corresponding different sizes for insertion in corresponding size cavities. ### Claim 21 (depends on 10) A device as in claim 10 wherein said upper portion of said marker is formed as a sphere to provide spherical symmetry and enable the same viewing image to be obtained in every direction. ### Claim 22 A device for marking body sites for imaging medical examination procedures comprising: fixtures adapted to be releasably fastened either to said body or to a stereotaxic means attached to said body; markers containing a substance which is contrasty in the imaging, said markers being adapted to be releasably fastened to said fixtures; and said fixtures being made of a material that does not disturb the imaging with at least two different imaging examination procedures.