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US 5,393,897 AGranted
Isolation and structure of spongistatins 5,7,8 and 9
AssigneeArizona Board of Regents acting on behalf of Arizona State University
InventorsGeorge R. Pettit, Zbigniew A. Cichacz, Cherry L. Herald
Life of this patent
Estimating the term…
Abstract
A Southwest Indian Ocean marine sponge Spirastrella spinispirulifera (bri colored reds and purples) has been found to contain new and exceptionally active cell (human cancer) growth inhibitors spongistatin 5, spongistatin 7, spongistatin 8 and spongistatin 9. These compositions are related to spongistatin 1, which was found in a black Spongia sp. in the Porifera family. A method of treating human cancer cells with spongistatin 5 and spongistatin 7 is also disclosed.
Claims6
A composition of matter having the following structure:
- ##STR63## wherein R=Cl or H and R.sub.1 =H or COCH.sub.3.
Dependencies are inferred from the claim text.