Method for treating inflammation, ischemia-induced cell damage and muscular dystrophy

A method of treating ischemia-induced cell damage in mammals which comprises administering to said mammal an effective amount of a compound, or a pharmaceutically acceptable salt thereof, of formula II ##STR28## wherein:

• R.sup.1 and R.sup.2 are each independently hydrogen, C.sub.1 -C.sub.6 alkyl C.sub.1 -C.sub.6 alkoxy or C.sub.1 -C.sub.4 ##STR29## R.sup.3 and R.sup.4 are each independently hydrogen or C.sub.1 -C.sub.4 alkyl;
• n is an integer from 1 to 4, both inclusive;
• and
• R.sup.5 and R.sup.6 are defined to be either:
• A) R.sup.5 and R.sup.6 are each independently hydrogen, C.sub.1 -C.sub.8 alkyl, C.sub.3 -C.sub.8 cycloalkyl, C.sub.2 -C.sub.8 alkenyl, C.sub.2 -C.sub.8 alkynyl, --(CH.sub.2).sub.q OR.sup.7, --(CH.sub.2).sub.q N(R.sup.7 R.sup.8), --(CH.sub.2).sub.q SR.sup.7, --(CH.sub.2).sub.r naphthyl or ##STR30## where q is an integer from 1 to 6, both inclusive, R.sup.7 and R.sup.8 are each independently hydrogen or C.sub.1 -C.sub.4 alkyl, R.sup.9 is hydrogen, halo, C.sub.1 -C.sub.4 alkyl, trifluoromethyl, hydroxy, amino, C.sub.1 -C.sub.4 alkylamino, di(C.sub.1 -C.sub.4 alkyl)amino, phenylamino or diphenylamino, and r is an integer from 0 to 4, both inclusive;
• or
• B) one of R.sup.5 or R.sup.6 is as defined in (A) above and the other is ##STR31## wherein n.sup.a, R.sup.1a, R.sup.2a, R.sup.3a and R.sup.4a are the same substituent as n, R.sup.1, R.sup.2, R.sup.3 and R.sup.4, respectively.