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US 5,393,744 AGranted
Glucosyl phosphotriesters of thymidine
AssigneeInstitut Pasteur
InventorsTam Huynh Dinh, Catherine Gouyette, Bernadette Dupraz, Jean Igolen, Nathalie Savatier, Jean-Francois Nicolas, Francoise Barre-Sinoussi
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Abstract
A compound having the following formula I: ##STR1## in which: R' represents a hydrogen atom or an azido group, alc represents an alkyl group of 1 to 4 carbon atoms, an alkoxy group of 1 to 4 carbon atoms or an amino group.
Claims10
A compound having the following formula I:
- ##STR12## in which:
- R' represents a hydrogen atom or an azido group,
- alc represents a saturated or unsaturated hydrocarbon radical of 5 to 30 carbon atoms optionally substituted by an alkyl group of 1 to 4 carbon atoms, an alkoxy group of 1 to 4 carbon atoms or an amine group.
A glucosyl phosphotriester thymidine compound which is 6-glucosyl hexadecyl 5'-(3'-azido) thymidinyl phosphate or 6-glucosyl hexadecyl 5'-(3'-deoxy) thymidinyl phosphate.
A glucosyl phosphodiester thymidine compound of the following formula (II):
- ##STR13## in which R' is a hydrogen or an azido group.
Dependencies are inferred from the claim text.