Liquid chromatography system
AssigneeZymark Corporation
InventorsBurleigh M. Hutchins, Raymond R. Dunlap, Timothy J. Conklin, Bruce A. Swanson, John Petracca, Louis Abrahams, Ronald A. Kimball
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Abstract
A liquid chromatography system including a liquid pump having a pumping chamber, an inlet port, an outlet port, and a purge port, all communicating with the pumping chamber; a separation column; an outlet valve connected between the outlet port and the separation column and adapted to control liquid flow therebetween; a source of mobile phase; an inlet valve connected between the inlet port and the source and adapted to control liquid flow therebetween; and a purge valve connected to the purge port.
Claims10
Liquid chromatography apparatus comprising:
- a liquid pump having a pumping chamber, an inlet port, an outlet port, and a purge port, all said ports communicating with said pumping chamber;
- a separation column;
- an outlet valve connected between said outlet port and said separation column and adapted to control liquid flow therebetween;
- a source of mobile phase;
- an inlet valve connected between said inlet port and said source and adapted to control liquid flow therebetween;
- and
- a purge valve connected to said purge port and operable to purge said pumping chamber.
Liquid chromatography apparatus comprising:
- a first liquid pump having a first pumping chamber, and a first inlet port and a first outlet port both communicating with said first pumping chamber;
- a separation column;
- a first outlet valve connected between said first outlet port and said column and adapted to control liquid flow therebetween;
- a source of mobile phase;
- a first inlet valve connected between said first inlet port and said source and adapted to control liquid flow therebetween;
- a second liquid pump having a second pumping chamber, and a second inlet port and a second outlet port communicating with said second pumping chamber;
- a second inlet valve connected between said second inlet port and said source and adapted to control liquid flow therebetween;
- a second outlet valve connected between said second outlet port and said column and adapted to control liquid flow therebetween;
- sensing means for monitoring the pumping performance of said first liquid pump;
- and
- control means responsive to said sensing means and operable to deactivate said first liquid pump and activate said second liquid pump in response to given deterioration in said pumping performance of said first liquid pump.
Dependencies are inferred from the claim text.