Stent sheath for local drug delivery
AssigneeEmory University
InventorsNeal A. Scott, Stephen R. Hanson, Spencer B. King, III, Laurence A. Harker
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Abstract
This invention provides a sheath for encompassing at least a portion of a stent to locally deliver a drug to an arterial wall or lumen into which the stent has been inserted, comprising a polymer and a drug incorporated within the polymer, the polymer sheath encompassing at least a portion of the stent and a thickness to allow controlled release of the drug. Also provided is a method of preventing thrombosis and promoting and inhibiting vascular growth in a subject comprising inserting a stent encompassed by the sheath of the invention into a vessel of the subject.
Claims25
In combination, a hollow tubular stent having a predetermined length and a separate sheath removably encompassing at least a portion of said hollow tubular stent to locally deliver at least one drug to an area selected from the group consisting of an arterial wall and an arterial lumen into which the stent has been inserted, comprising at least one polymer and at least one drug incorporated within the polymer, the sheath removably encompassing at least a portion of the stent and having a thickness to allow controlled release of the drug.
A kit comprising a hollow tubular stent and a separate sheath for removably encompassing at least a portion of the stent to locally deliver at least one drug to an area selected from the group consisting of an arterial wall and an arterial lumen into which the stent has been inserted, comprising at least one polymer and at least one drug incorporated within the polymer, the sheath removably encompassing at least a portion of the stent and having a thickness to allow Controlled release of the drug.
Dependencies are inferred from the claim text.