3,3-diphenylpropylamines and pharmaceutical compositions thereof
AssigneePharmacia Aktiebolag
InventorsNils A. Jonsson, Bengt A. Sparf, Lembit Mikiver, Pinchas Moses, Lisbet Nilvebrant, Gunilla Glas
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Abstract
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Claims7
3,3-Diphenylpropylamines of formula I ##STR31## wherein R.sup.1 signifies hydrogen or methyl, R.sup.2, R.sup.3 and R.sup.4 independently signify hydrogen, methyl, methoxy, hydroxy, carbamoyl, sulphamoyl or halogen, and X represents a tertiary amino group of formula II ##STR32## wherein each of R.sup.5 and R.sup.6 independently signifies C.sub.1-6 alkyl, which may be joined to form a non-aromatic ring having no hetero atom other than the amine nitrogen and each of which may carry a hydroxy substituent, or adamantyl, and wherein R.sup.5 and R.sup.6 together contain at least four carbon atoms, their salts with physiologically acceptable acids and, when the compounds can be in the form of optical isomers, the racemic mixture and the individual enantiomers.
Dependencies are inferred from the claim text.