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US 5,378,467 AGranted
Cell-free Marek's disease virus vaccine
AssigneeAkzo N.V.
InventorWilliam Bexendale
Life of this patent
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Abstract
The present invention is concerned with a vaccine for the protection of poultry against Marek's Disease. The cell free vaccine of the invention facilitates the handling of the vaccine and reduces the chance of physical abuse. The invention also relates to bivalent or polyvalent vaccines comprising in addition other viruses of the Marek's Disease virus group, i.e. HVT.
Claims14
A vaccine for the protection of poultry against Marek's Disease, comprising cell-free Marek's Disease serotype 2 virus, and a pharmaceutically acceptable carrier.
A method for the preparation of a vaccine that protects poultry against Marek's Disease comprising:
- a) growing a serotype 2 Marek's Disease virus in a cell culture from which sufficient quantities of cell-free virus
- necessary to prepare an effective immunizing dosage can be obtained,
- b) disrupting the cells, and
- c) collecting the cell-free viruses, and mixing them with cell-free HVT,
- such as to prepare an effective immunizing dosage of said vaccine.
2 more elements
Dependencies are inferred from the claim text.