Support material for cell impregnation
AssigneeUnited States Surgical Corporation
InventorsDonald S. Kaplan, John Kennedy, Ross R. Muth, Elliot A. Gruskin
Life of this patent
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Abstract
A support material for cell impregnation is provided. The support material is fabricated from a semiabsorbable composite yarn comprising a nonabsorbable, elastic core yarn and an absorbable, relatively inelastic sheath yarn. A prosthetic device may be formed from the support material. The support material is impregnated with living cells followed by incorporation into the tissue structure of a host organism. The support material impregnated with cells may be cultured in vitro to increase the number of cells prior to incorporation into the host organism.
Claims21
An impregnated support material comprising:
- a support material fabricated from semiabsorbable, composite yarn comprising a nonabsorbable, elastic core yarn imparting resiliency to the composite yarn and at least one absorbable, relatively inelastic sheath yarn imparting transverse strength to the composite yarn;
- living cells contacting an exterior portion of the composite yarn of the support material in vitro.
A method of impregnating a support material comprising:
- providing a semiabsorbable, composite yarn comprising a nonabsorbable, elastic core yarn imparting resiliency to the composite yarn and at least one absorbable, relatively inelastic sheath yarn imparting transverse strength to the composite yarn;
- forming a support material from the composite yarn;
- and
- contacting the support material with living cells in vitro such that cells contact the composite yarn.
Dependencies are inferred from the claim text.